The Institute of Molecular and Clinical Ophthalmology Basel (IOB) is seeking a highly motivated
Research Assistant to join the Complex Viruses Platform for an 8-month maternity leave
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IOB is a research institute combining basic and clinical research. Its mission is to drive innovations in understanding vision and its diseases and develop new therapies for vision loss.
One of the goals of the Complex Viruses Platform is to produce viral vectors for research
groups at the IOB. The profile of the Platform is service oriented but open-minded for establishment of new technologies and processes. The Research Assistant of the Complex Viruses Platform will be responsible for generation and quality control of AAV plasmid DNA, AAV production in adherent and suspension mammalian cell culture, purification by affinity chromatography, and quality control.

Your responsibilities

Generation of plasmid DNA using standard cloning techniques and latest recombination techniques.
Production of plasmid DNA in bacteria cultures including plasmid purification and characterization.
Production of AAV by using specific cell culture systems.
Purification of AAV particles.
Quantification and efficiency tests of AAV preparations, including titration by qPCR and ddPCR, transduction and efficiency testing in retinal organoids.
Involvement in lab management and organization.
Close collaboration with platform members and IOB research groups.

Requirements

Biology lab assistant (or equivalent education) or Bachelor’s/Master’s Degree (or equivalent) in molecular biology or related field.
Independence in the planning, realization, analysis and troubleshooting of standard molecular biology experiments.
Enthusiasm to establish and optimize new protocols and techniques.
Highly organized, detail-oriented and skilled with computer-based work.
Willingness to work under biosafety level 2 (BL2) laboratory condition.
Excellent written and oral communication skills in English.

We offer

Join a groundbreaking research institute where your contributions advance the frontiers of ophthalmology and medical science. Beyond meaningful work, you'll enjoy:

Competitive academic sector compensation that recognizes your expertise and contributions
Generous time off including five weeks of annual vacation, with additional days increasing with age in accordance with Swiss employment standards
Comprehensive parental support with up to 16 weeks paid maternity leave and flexible options to extend your time with your family
Opportunities for unpaid leave when life requires it
Opportunities for professional growth and development, including training and education support
Family-friendly culture featuring childcare subsidies and a dedicated family room, because we know your family matters
Lifestyle perks including subsidized cafeteria meals, access to University of Basel sports facilities, and exclusive employee discounts
Collaborative environment where innovation thrives and your work contributes to breakthrough discoveries in vision science

Application / Contact

To apply, please submit your application through our recruiting platform (Link). For more information, visit www.iob.ch. If you have questions after applying, you can contact us by simply replying to the confirmation email you will receive.

Please note that we only accept applications via the recruiting portal.

Contact

Human Resources
Recruiting team
IOB - Institute of Molecular and Clinical Ophthalmology Basel

Molecular Biology Research Assistant (Temporary 8-month position - April 2026) 80-100%

Your responsibilities

Requirements

We offer

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